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Phenytoin-Induced Gingival Enlargement
*Corresponding author: Kriti Bhat, Department of Dermatology, Venereology and Leprosy, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India. Kritibhat1996@gmail.com
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Received: ,
Accepted: ,
How to cite this article: Kayarkatte MN, Puri V, Bhat K. Phenytoin-Induced Gingival Enlargement. Indian J Postgrad Dermatol. doi: 10.25259/IJPGD_240_2024
A 22-year-old male presented with complaints of gingival hypertrophy [Figure 1] associated with poor dental hygiene since past 5 years. He was a known case of epilepsy and had been treated with phenytoin since past 7 years.
- Phenytoin-induced gingival enlargement.
Drug-induced gingival enlargement is an adverse effect of three main classes of drugs: anticonvulsants, antihypertensive calcium channel blockers and the immunosuppressant cyclosporine. The prevalence of phenytoin-induced gingival overgrowth is variable ranging from 13% to 50%. Classically, it begins in the interdental papillae within the 1st month of starting phenytoin and increases to its maximum by 1 year. It affects chewing, speech and is also cosmetically disfiguring.
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Conflicts of interest
There are no conflicts of interest.
Use of artificial intelligence (AI)-assisted technology for manuscript preparation
The authors confirm that there was no use of artificial intelligence (AI)-assisted technology for assisting in the writing or editing of the manuscript and no images were manipulated using AI.
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