Quiz on Autoimmune Vesiculobullous Disorders

S. Dinesh Kumar; J. Iswariya; Debdeep Mitra

doi:10.25259/IJPGD_97_2024

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Quiz

3 (

1

); 113-114

doi:

10.25259/IJPGD_97_2024

Quiz on Autoimmune Vesiculobullous Disorders

S. Dinesh Kumar^1,, J. Iswariya², Debdeep Mitra¹

1Department of Dermatology, Venereology and Leprosy, Command Hospital Airforce, Bengaluru, Karnataka, India

2Department of Dermatology, Command Hospital Airforce, Bengaluru, Karnataka, India.

*Corresponding author: S. Dinesh Kumar, Department of Dermatology, Venereology and Leprosy, Command Hospital Air Force, Bengaluru, Karnataka, India. dheenumbbs@gmail.com

Received: 2024-05-28, Accepted: 2024-11-17, Epub ahead of print: 2025-01-13, Published: 2025-02-07

Licence

This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, transform, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

How to cite this article: Dinesh Kumar S, Iswariya J, Mitra D. Quiz on Autoimmune Vesiculobullous Disorders. Indian J Postgrad Dermatol. 2025;3:113-4. doi: 10.25259/IJPGD_97_2024

QUESTIONS

What does the term ‘maculae adherentes’ denote?^[1]
Which lymphoproliferative disorder is most commonly associated with paraneoplastic pemphigus in children?^[2]
Name the salivary antigen in black fly that causes fogo selvagem.^[3]
Which type of mucous membrane pemphigoid is associated with internal adenocarcinoma?^[4]
Which immunoglobulin subclass is significantly expressed in pemphigus vulgaris patients during remission?^[5]
Name the fluorochrome used in immunofluorescence techniques which produce red colour.^[6]
Name the dermatologist who was the first to distinguish bullous pemphigoid as a separate entity from pemphigus vulgaris.^[7]
Which is the recommended substrate for indirect immunofluorescence in pemphigus foliaceus other than human skin?^[8]
Name the eponymous sign which indicates cerebriform tongue in pemphigus vegetans.^[9]
How much magnification is required for serration analysis?^[10]
Which body parts are typically affected in Brunsting-Perry pemphigoid?^[11]
Name the target antigen in chronic bullous disease of childhood.^[12]
Which antigen is the target in bullous systemic lupus erythematosus?^[13]
Which subepidermal blistering disorder is characterised by exclusive staining of basement membrane zone with C3?^[14]
Mention the direct immunofluorescence (DIF) finding in atypical dermatitis herpetiformis.^[15]
Which other specimen can be used for DIF in a suspected case of autoimmune vesiculobullous disorder if the patient refuses to have a skin biopsy?^[16]
Paraneoplastic pemphigus targets all of the protiens listed here, with the exception of^[17]
1. Bullous pemphigoid antigen 1 (BPAG1)
2. Periplakin
3. Envoplakin
4. Bullous pemphigoid antigen 2 (BPAG2)
Which Human leukocyte antigen (HLA) is strongly associated with dermatitis herpetiformis?^[18]
How long is the immunogenicity preserved in Michel’s medium?^[19]

Match the following drugs that have been linked to autoimmune vesiculobullous disorders.^[20]

a) Vancomycin	(i) Cicatricial pemphigoid
b) Dipeptidyl peptidase-4 inhibitors	(ii) Linear immunoglobulin A (IgA) bullous dermatosis
c) Penicillamine	(iii) Bullous pemphigoid
d) Clonidine	(iv) Pemphigus foliaceus

ANSWERS

Desmosome
Castleman disease
Lutzomyia longipalpis salivary protein 11
Anti-epiligrin mucous membrane pemphigoid
Immunoglobulin G 1
Tetramethylrhodamine isothiocyanate
Walter fredrick lever
Guinea pig oesophagus
Premlatha sign
>600 fold
Head and neck
97kDa portion of bullous pemphigoid antigen 2 (BPAG2)
Collagen VII
Pemphigoid gestationis
Fibrillary IgA deposition at basement membrane zone
Outer root sheeth of anagen hair
d
Human leukocyte antigen (HLA) DQ2
6 months
(a)-ii (b)-iii (c)-iv (d)-i

Ethical approval

Institutional Review Board approval is not required.

Declaration of patient consent

Patient’s consent not required as there are no patients in this study.

Conflicts of interest

There are no conflicts of interest.

Use of artificial intelligence (AI)-assisted technology for manuscript preparation

The authors confirm that there was no use of artificial intelligence (AI)-assisted technology for assisting in the writing or editing of the manuscript and no images were manipulated using AI.

Financial support and sponsorship

Nil.

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