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A Case of the Suspicious Horn
*Corresponding author: Bartika Sikder, Department of Dermatology, Prafulla Chandra Sen Medical College and Hospital, Arambagh, West Bengal, India. bartikasikder@gmail.com
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Received: ,
Accepted: ,
How to cite this article: Gorai S, Sikder B, Dey S. A Case of the Suspicious Horn. Indian J Postgrad Dermatol. doi: 10.25259/IJPGD_154_2025
A 65-year-old man presented with a 15-year history of a slowly growing, asymptomatic chest lesion. Examination revealed a 5 cm curved, hard keratin column with vertical ridges and an ‘oyster-shell’ appearance. At its base was a firm, erythematous, non-tender nodule with telangiectasia, fixed to the underlying skin [Figure 1]. No lymphadenopathy was noted. A clinical diagnosis of cutaneous horn overlying squamous cell carcinoma was made. Excision and subsequent histopathology showed epithelial cell nests with eosinophilic cytoplasm extending up to varying depths into the dermis, along with horn pearls [Figure 2]. Margins were clear of atypia. The patient was counselled and advised to undergo 3-monthly follow-ups.

- A 5 cm long, curved, hard keratin column with vertical ridges and an ‘oyster-shell’ appearance. The base comprised of a firm, erythematous, non-tender nodule with telangiectasia, fixed to the underlying skin.

- Histopathological image (10x magnification) shows epithelial cell nests with eosinophilic cytoplasm and nuclear atypia extending up to varying depths into the dermis (red circle), along with horn pearls (black arrows).
Ethical approval:
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Declaration of patient consent:
The authors certify that they have obtained all appropriate patient consent.
Conflicts of interest:
There are no conflicts of interest.
Use of artificial intelligence (AI)-assisted technology for manuscript preparation:
The authors confirm that there was no use of artificial intelligence (AI)-assisted technology for assisting in the writing or editing of the manuscript and no images were manipulated using AI.
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